https://darkmatter.ucsf.edu/ en https://darkmatter.ucsf.edu/data-mining/disease-data-tmc7 <span class="field field--name-title field--type-string field--label-hidden">Disease Data for TMC7</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/user/11" typeof="schema:Person" property="schema:name" datatype="">ctran</span></span> <span class="field field--name-created field--type-created field--label-hidden">Tue, 03/16/2021 - 12:45</span> <div class="field field--name-field-10k-immunome field--type-entity-reference field--label-above"> <div class="field__label">10K Immunome:</div> <div class="field__item"><a href="/taxonomy/term/3556" hreflang="en">Not Detected</a></div> </div> <div class="field field--name-field-sars-cov-2-association field--type-entity-reference field--label-above"> <div class="field__label">SARS-CoV-2 Association:</div> <div class="field__item"><a href="/taxonomy/term/3561" hreflang="en">Not Detected</a></div> </div> <div class="field field--name-field-sars-cov-2-vaccine-associa field--type-entity-reference field--label-above"> <div class="field__label">SARS-CoV-2 Vaccine Association:</div> <div class="field__item"><a href="/taxonomy/term/3566" hreflang="en">Not Detected</a></div> </div> <div class="field field--name-field-gene-taxonomy field--type-entity-reference field--label-inline"> <div class="field__label">Gene Taxonomy:</div> <div class="field__item"><a href="/gene/tmc7" hreflang="en">TMC7</a></div> </div> <div class="field field--name-field-uniprotid field--type-string field--label-inline"> <div class="field__label">UniprotID:</div> <div class="field__item">Q7Z402</div> </div> <div class="field field--name-field-mouse-homolog field--type-string field--label-inline"> <div class="field__label">Mouse Homolog:</div> <div class="field__item">Tmc7</div> </div> <div class="field field--name-field-pharos-link field--type-link field--label-inline"> <div class="field__label">Pharos Link:</div> <div class="field__item"><a href="https://pharos.nih.gov/targets/Q7Z402">Pharos Link</a></div> </div> <div class="field field--name-field-knockout-mouse-phenotype field--type-entity-reference field--label-inline"> <div class="field__label">Knockout Mouse Phenotype:</div> <div class="field__items"> <div class="field__item"><a href="/knockout-mouse-phenotype/male-infertility" hreflang="x-default">Male infertility</a></div> <div class="field__item"><a href="/knockout-mouse-phenotype/female-infertility" hreflang="x-default"> Female infertility</a></div> </div> </div> <div class="field field--name-field-monogenic-disease-associat field--type-entity-reference field--label-inline"> <div class="field__label">Monogenic Disease Association:</div> <div class="field__items"> <div class="field__item"><a href="/taxonomy/term/3496" hreflang="x-default">Not Detected</a></div> </div> </div> <div class="field field--name-field-polygenic-disease-associat field--type-entity-reference field--label-inline"> <div class="field__label">Polygenic Disease Association:</div> <div class="field__items"> <div class="field__item"><a href="/polygenic-disease-association/not-detected" hreflang="x-default">Not Detected</a></div> </div> </div> Tue, 16 Mar 2021 19:45:54 +0000 ctran 14892 at https://darkmatter.ucsf.edu https://darkmatter.ucsf.edu/expression/expression-tmc7-dorsal-root-ganglion <span class="field field--name-title field--type-string field--label-hidden">Expression of Tmc7 in Dorsal Root Ganglion</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/user/16" typeof="schema:Person" property="schema:name" datatype="">zicheng</span></span> <span class="field field--name-created field--type-created field--label-hidden">Thu, 02/06/2020 - 17:20</span> <div class="field field--name-field-normal-tissue-image field--type-image field--label-above"> <div class="field__label">Normal Tissue Image:</div> <div class="field__item"> <a href="https://darkmatter.ucsf.edu/sites/darkmatter.ucsf.edu/files/2020-02/tmc7_green_wt_20x.jpg" aria-controls="colorbox" aria-label="{&quot;alt&quot;:&quot;Tmc7&quot;}" role="button" title="Tmc7" data-colorbox-gallery="gallery-in_situ_expression-11231-TvB0s_EFySM" class="colorbox" data-cbox-img-attrs="{&quot;alt&quot;:&quot;Tmc7&quot;}"><img src="/sites/darkmatter.ucsf.edu/files/styles/large/public/2020-02/tmc7_green_wt_20x.jpg?itok=GYa5L_Nj" width="480" height="480" alt="Tmc7" loading="lazy" typeof="foaf:Image" class="image-style-large" /> </a> </div> </div> <div class="field field--name-field-expression-level-compariso field--type-image field--label-above"> <div class="field__label">Expression level comparison:</div> <div class="field__item"> <a href="https://darkmatter.ucsf.edu/sites/darkmatter.ucsf.edu/files/2020-02/tmc7_graph.jpg" aria-controls="colorbox" aria-label="{&quot;alt&quot;:&quot;Tmc7&quot;}" role="button" title="Tmc7" data-colorbox-gallery="gallery-in_situ_expression-11231-TvB0s_EFySM" class="colorbox" data-cbox-img-attrs="{&quot;alt&quot;:&quot;Tmc7&quot;}"><img src="/sites/darkmatter.ucsf.edu/files/styles/large/public/2020-02/tmc7_graph.jpg?itok=Y5Fx97H_" width="480" height="480" alt="Tmc7" loading="lazy" typeof="foaf:Image" class="image-style-large" /> </a> </div> </div> <div class="field field--name-field-gene-taxonomy field--type-entity-reference field--label-inline"> <div class="field__label">Gene Taxonomy:</div> <div class="field__item"><a href="/gene/tmc7" hreflang="en">TMC7</a></div> </div> <div class="field field--name-field-injury field--type-entity-reference field--label-inline"> <div class="field__label">Injury Type:</div> <div class="field__item"><a href="/taxonomy/term/3531" hreflang="en">Tissue Injury</a></div> </div> <div class="field field--name-field-injured-tissue-image field--type-image field--label-above"> <div class="field__label">Injured Tissue Image:</div> <div class="field__item"> <a href="https://darkmatter.ucsf.edu/sites/darkmatter.ucsf.edu/files/2020-02/tmc7_green_injury_20x.jpg" aria-controls="colorbox" aria-label="{&quot;alt&quot;:&quot;Tmc7&quot;}" role="button" title="Tmc7" data-colorbox-gallery="gallery-in_situ_expression-11231-TvB0s_EFySM" class="colorbox" data-cbox-img-attrs="{&quot;alt&quot;:&quot;Tmc7&quot;}"><img src="/sites/darkmatter.ucsf.edu/files/styles/large/public/2020-02/tmc7_green_injury_20x.jpg?itok=XYz2PeqX" width="480" height="480" alt="Tmc7" loading="lazy" typeof="foaf:Image" class="image-style-large" /> </a> </div> </div> <div class="field field--name-field-neuron-type field--type-entity-reference field--label-inline"> <div class="field__label">Neuron Type:</div> <div class="field__item"><a href="/taxonomy/term/3521" hreflang="en">Dorsal Root Ganglion</a></div> </div> <div class="field field--name-field-tissue field--type-string field--label-inline"> <div class="field__label">Tissue:</div> <div class="field__item">DRG<br /> <br /> </div> </div> <div class="field field--name-field-conditions field--type-string field--label-inline"> <div class="field__label">Conditions:</div> <div class="field__item">naive vs injury (SNI 7days)<br /> <br /> </div> </div> <div class="field field--name-field-probe field--type-string field--label-inline"> <div class="field__label">Probe:</div> <div class="field__item">Probe Mm-Tmc7 #592331 At Advanced Cell Diagnostics<br /> <br /> </div> </div> <div class="field field--name-field-species field--type-string field--label-inline"> <div class="field__label">Species:</div> <div class="field__item">Mouse<br /> <br /> </div> </div> Fri, 07 Feb 2020 01:20:24 +0000 zicheng 11231 at https://darkmatter.ucsf.edu https://darkmatter.ucsf.edu/constructs/idg_tmc7_oe_1 <span class="field field--name-title field--type-string field--label-hidden">Lentiviral Construct for TMC7</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/user/16" typeof="schema:Person" property="schema:name" datatype="">zicheng</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 10/30/2019 - 11:24</span> <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <a href="https://darkmatter.ucsf.edu/sites/darkmatter.ucsf.edu/files/2021-03/D.IC60-pLX304-TMC7-expression-vector%20Map.png" aria-controls="colorbox" aria-label="{&quot;alt&quot;:&quot;&quot;}" role="button" title="Lentiviral Construct for TMC7" data-colorbox-gallery="gallery-dna_constructs-10101-TvB0s_EFySM" class="colorbox" data-cbox-img-attrs="{&quot;alt&quot;:&quot;&quot;}"><img src="/sites/darkmatter.ucsf.edu/files/styles/medium/public/2021-03/D.IC60-pLX304-TMC7-expression-vector%20Map.png?itok=Sybn39ZO" width="220" height="196" alt="" loading="lazy" typeof="foaf:Image" class="image-style-medium" /> </a> </div> <div class="field field--name-field-inserted-sequence field--type-string field--label-above"> <div class="field__label">Inserted_sequence:</div> <div class="field__item">ATGAGCGAGTCCAGCGGCAGTGCGCTCCAGCCCGGCAGGCCCAGCCGGCAGCCGGCGGTCCATCCAGAGAACCTCTCTCT<br /> AGACTCCAGTTGCTTCTCTTCTCCACCTGTGAACTTCCTCCAAGAATTGCCAAGCTACCGGTCCATTGCACGTAGGAGAA<br /> CGACTGTCCATTCCTGGGACAAGCAAAGCGGAACTTTGCTAAAGCCAACCGACTCTTACAGCTCCCAGCTGGAGGACAGA<br /> ATCGCTGAAAACCTCAGCAGCCATTCTCTTCGAAATTATGCACTGAACATCTCTGAGAAGCGGAGACTAAGGGACATTCA<br /> AGAGACACAAATGAAGTATCTCTCCGAATGGGACCAGTGGAAGCGGTATAGCAGCAAGTCTTGGAAGAGGTTCCTAGAGA<br /> AGGCTCGAGAGATGACGACCCACCTGGAGCTGTGGCGGGAGGACATCCGCAGCATAGAAGGGAAATTTGGCACTGGGATT<br /> CAGTCCTATTTCTCCTTCTTGAGATTCCTGGTGTTGCTGAATTTGGTGATATTTCTGATCATCTTTATGCTGGTTTTGCT<br /> CCCAGTCTTACTCACGAAATACAAGATCACCAACAGCAGCTTCGTGCTCATTCCTTTCAAAGACATGGATAAACAATGTA<br /> CAGTCTATCCAGTAAGCAGTTCTGGACTCATTTACTTTTACAGTTATATCATAGACTTGCTTTCTGGCACTGGTTTCCTG<br /> GAGGAAACTAGCCTCTTTTACGGACATTACACCATTGATGGGGTGAAATTTCAGAACTTCACCTATGATCTGCCCCTGGC<br /> GTATTTGTTAAGCACAATCGCCTCCCTGGCCCTGAGCCTTCTTTGGATAGTGAAAAGGTCGGTGGAAGGATTCAAAATCA<br /> ACCTGATTCGGAGTGAGGAGCACTTTCAGAGTTACTGCAACAAGATATTTGCCGGCTGGGACTTCTGCATCACTAACCGC<br /> AGCATGGCGGATCTGAAGCACAGCAGCTTGCGGTACGAGCTCCGAGCAGATCTGGAGGAAGAAAGAATGCGGCAGAAAAT<br /> AGCAGAAAGGACCTCAGAAGAAACAATACGCATTTACTCTTTGAGACTGTTTTTGAACTGTATTGTTCTGGCTGTTTTAG<br /> GGGCATGCTTTTATGCAATATACGTAGCAACTGTCTTCTCGCAAGAGCACATGAAAAAGGAAATCGACAAGATGGTTTTT<br /> GGAGAGAACCTCTTCATATTGTATCTACCGTCTATTGTGATCACGCTGGCCAATTTTATCACCCCAATGATCTTTGCCAA<br /> GATCATCCGCTATGAGGATTATTCTCCAGGCTTTGAGATCCGTCTGACAATCCTTAGGTGTGTCTTTATGCGGCTGGCCA<br /> CCATATGTGTCCTGGTGTTCACGCTGGGCTCCAAGATCACATCCTGTGATGATGACACATGTGACCTTTGCGGCTACAAC<br /> CAGAAACTCTACCCGTGCTGGGAGACCCAAGTTGGGCAGGAAATGTACAAGCTGATGATCTTCGACTTCATCATCATCTT<br /> GGCTGTGACACTCTTCGTGGATTTTCCTAGAAAGCTCCTGGTGACCTACTGTTCCTCTTGCAAGCTGATTCAGTGCTGGG<br /> GGCAGCAGGAGTTTGCCATTCCTGATAACGTCCTGGGGATAGTTTACGGGCAAACCATCTGCTGGATCGGAGCCTTTTTC<br /> TCACCCCTTCTCCCTGCAATTGCAACCCTGAAATTCATTATCATCTTCTATGTGAAAGAGTGGAGTCTGCTTTACACCTG<br /> CAGACCCTCCCCCAGGCCGTTCAGAGCATCCAATTCTAATTTCTTCTTCCTGTTGGTGTTGTTGATCGGGCTGTGTTTGG<br /> CAATAATACCTCTGACAATCAGCATATCACGCATCCCTTCCTCGAAAGCCTGTGGGCCGTTCACCAACTTCAACACCACC<br /> TGGGAGGTCATCCCCAAGACAGTGAGCACCTTCCCCAGCTCGCTGCAGTCCTTCATCCATGGTGTCACATCCGAAGCCTT<br /> TGCAGTTCCTTTCTTCATGATTATTTGCCTCATCATGTTTTACTTCATTGCCTTAGCTGGAGCACACAAACGGGTGGTCA<br /> TCCAGCTCCGAGAGCAGCTATCCCTGGAAAGTCGTGACAAGTGCTACCTAATCCAGAAACTAACAGAAGCCCAAAGGGAC<br /> ATGAGGAACTACCCAACTTTCTTGTACAAAGTGGTTGGTAAGCCTATCCCTAACCCTCTCCTCGGTCTCGATTCTACGTA<br /> G<br /> <br /> </div> </div> <div class="field field--name-field-snapgene-file field--type-file field--label-above"> <div class="field__label">Snapgene File:</div> <div class="field__item"> <span class="file file--mime-application-octet-stream file--general"> <a href="/sites/darkmatter.ucsf.edu/files/2021-03/D.IC60-pLX304-TMC7-expression-vector.dna" type="application/octet-stream">D.IC60-pLX304-TMC7-expression-vector.dna</a></span> </div> </div> <div class="field field--name-field-gene-taxonomy field--type-entity-reference field--label-inline"> <div class="field__label">Gene Taxonomy:</div> <div class="field__item"><a href="/gene/tmc7" hreflang="en">TMC7</a></div> </div> <div class="field field--name-field-virus-type field--type-entity-reference field--label-inline"> <div class="field__label">Virus Type:</div> <div class="field__item"><a href="/taxonomy/term/3511" hreflang="en">Lentiviral Vector</a></div> </div> <div class="field field--name-field-vector-type field--type-entity-reference field--label-inline"> <div class="field__label">Vector Type:</div> <div class="field__item"><a href="/taxonomy/term/3506" hreflang="en">cDNA</a></div> </div> <div class="field field--name-field-title field--type-string field--label-inline"> <div class="field__label">Construct ID:</div> <div class="field__item">IDG_TMC7_OE_1<br /> <br /> </div> </div> <div class="field field--name-field-selection-txt field--type-string field--label-inline"> <div class="field__label">Selection:</div> <div class="field__item">Amp, Blasticidin<br /> <br /> </div> </div> <div class="field field--name-field-vector-txt field--type-string field--label-inline"> <div class="field__label">Vector:</div> <div class="field__item">lPX304<br /> <br /> </div> </div> <div class="field field--name-field-construct-type field--type-string field--label-inline"> <div class="field__label">Construct Type:</div> <div class="field__item">Expression<br /> <br /> </div> </div> <div class="field field--name-field-tag field--type-string field--label-inline"> <div class="field__label">Tag:</div> <div class="field__item">C terminal V5<br /> <br /> </div> </div> <div class="field field--name-field-construct-passed-qc field--type-string field--label-inline"> <div class="field__label">Passed QC:</div> <div class="field__item">Yes<br /> <br /> </div> </div> Wed, 30 Oct 2019 18:24:50 +0000 zicheng 10101 at https://darkmatter.ucsf.edu https://darkmatter.ucsf.edu/crispri/idg_tmc7_ue_1 <span class="field field--name-title field--type-string field--label-hidden">CRISPRI Construct for TMC7</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/user/11" typeof="schema:Person" property="schema:name" datatype="">ctran</span></span> <span class="field field--name-created field--type-created field--label-hidden">Mon, 09/23/2019 - 14:11</span> <div class="field field--name-field-gene-taxonomy field--type-entity-reference field--label-inline"> <div class="field__label">Gene Taxonomy:</div> <div class="field__item"><a href="/gene/tmc7" hreflang="en">TMC7</a></div> </div> <div class="field field--name-field-image field--type-image field--label-above"> <div class="field__label">Vector Map:</div> <div class="field__item"> <a href="https://darkmatter.ucsf.edu/sites/darkmatter.ucsf.edu/files/2021-03/H6-783-TMC7-interference-vector%20Map.png" aria-controls="colorbox" aria-label="{&quot;alt&quot;:&quot;&quot;}" role="button" title="CRISPRI Construct for TMC7" data-colorbox-gallery="gallery-crispri_construct-7006-TvB0s_EFySM" class="colorbox" data-cbox-img-attrs="{&quot;alt&quot;:&quot;&quot;}"><img src="/sites/darkmatter.ucsf.edu/files/styles/medium/public/2021-03/H6-783-TMC7-interference-vector%20Map.png?itok=I1fGJtpR" width="220" height="203" alt="" loading="lazy" typeof="foaf:Image" class="image-style-medium" /> </a> </div> </div> <div class="field field--name-field-inserted-sequence field--type-string field--label-inline"> <div class="field__label">Inserted_sequence:</div> <div class="field__item">GGCCGAGCCGTGATGAGCGA</div> </div> <div class="field field--name-field-snapgene-file field--type-file field--label-above"> <div class="field__label">Snapgene File:</div> <div class="field__item"> <span class="file file--mime-application-octet-stream file--general"> <a href="/sites/darkmatter.ucsf.edu/files/2021-03/H6-783-TMC7-interference-vector.dna" type="application/octet-stream">H6-783-TMC7-interference-vector.dna</a></span> </div> </div> <div class="field field--name-field-title field--type-string field--label-inline"> <div class="field__label">Construct ID:</div> <div class="field__item">IDG_TMC7_UE_1</div> </div> <div class="field field--name-field-virus-type field--type-entity-reference field--label-inline"> <div class="field__label">Virus Type:</div> <div class="field__item"><a href="/taxonomy/term/3511" hreflang="en">Lentiviral Vector</a></div> </div> <div class="field field--name-field-selection field--type-list-string field--label-inline"> <div class="field__label">Selection:</div> <div class="field__item">Puro,Amp</div> </div> <div class="field field--name-field-vector field--type-list-string field--label-inline"> <div class="field__label">Vector:</div> <div class="field__item">783_hU6_EGFP</div> </div> <div class="field field--name-field-passed-qc field--type-boolean field--label-inline"> <div class="field__label">Passed QC:</div> <div class="field__item">On</div> </div> <div class="field field--name-field-vector-type field--type-entity-reference field--label-inline"> <div class="field__label">Vector Type:</div> <div class="field__item"><a href="/taxonomy/term/3516" hreflang="en">CRISPR Interference</a></div> </div> Mon, 23 Sep 2019 21:11:36 +0000 ctran 7006 at https://darkmatter.ucsf.edu