Loading...

Disease Data for CLIC5

Basic Information

Gene Taxonomy:
CLIC5
UniprotID:
Q9NZA1
Mouse Homolog:
Clic5
Pharos Link:
Pharos Link
Knockout Mouse Phenotype:
decreased body size
circling
Hyperactivity
abnormal renal glomerulus morphology
Gait disturbance
Abnormal renal physiology
decreased circulating glucose level
Polyphagia
Albuminuria
Proteinuria
Adipose tissue loss
Hypoinsulinemia
Decreased serum leptin
Neutropenia
Lethargy
Hearing impairment
Hypothermia
Osteopenia
Monocytopenia
Gastrointestinal hemorrhage
decreased bone mineral content
decreased prepulse inhibition
decreased body length
increased or absent threshold for auditory brainstem response
decreased eosinophil cell number
decreased startle reflex
increased respiratory quotient
absent startle reflex
head bobbing
abnormal pulmonary alveolus morphology
abnormal lens development
vestibular hair cell degeneration
increased susceptibility to weight loss
cochlear ganglion degeneration
podocyte foot process effacement
cochlear outer hair cell degeneration
head tossing
decreased susceptibility to hepatic steatosis
organ of Corti degeneration
increased susceptibility to injury
bidirectional circling
impaired swimming
abnormal cochlear hair cell stereociliary bundle morphology
increased circulating glucagon level
increased stomach pH
cochlear inner hair cell degeneration
increased aggression towards males
abnormal glomerular capillary endothelium morphology
abnormal podocyte foot process morphology
decreased digestive secretion
abnormal glomerular endothelium fenestra morphology
Monogenic Disease Association:
Not Detected
Polygenic Disease Association:
leukocyte count
10K Immunome:
Not Detected
SARS-CoV-2 Association:
Not Detected
SARS-CoV-2 Vaccine Association:
Not Detected
© University of California.
Exploring the Dark Genome