Dark Gene Expression in Sensory and Spinal Cord Neurons

About this resource As part of the IDG Mission of providing resources for scientific community to enable study of the dark genes, we characterized and quantified the expression levels of the dark genes in subsets of sensory (dorsal root ganglion; DRG) and spinal cord neurons, both in naive conditions (wild-type mice) as well as in the setting of neuropathic and inflammatory chronic pain.

How this recourse was generated? We performed fluorescent multiplex in situ hybridization on DRG and spinal cord tissue harvested from wild-type mice as well as 7 days after peripheral nerve cut (neuropathic pain condition) or 3 days after hindpaw injection of complete freund’s adjuvant (inflammatory condition). Quantification was performed using Image J.

Where this resource can be requested These data are available below-- and if you need additional data or would be interested in collaborating on pain-related phenotypes, please contact us. If you have commercial interests, please include this in your email query.