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Data and Resources for CACNB3 Gene

Disease Associated Data

Basic Information

Gene Taxonomy:
CACNB3
UniprotID:
P54284
Mouse Homolog:
Cacnb3
Pharos Link:
Pharos Link
Knockout Mouse Phenotype:
vision/eye phenotype
nervous system phenotype
abnormal calcium ion homeostasis
Cardiomegaly
increased heart weight
decreased interferon-gamma secretion
enhanced long term potentiation
abnormal discrimination learning
abnormal long term object recognition memory
abnormal sensory neuron innervation pattern
increased systemic arterial diastolic blood pressure
enhanced contextual conditioning behavior
abnormal channel response
increased systemic arterial blood pressure
abnormal CD4-positive
alpha-beta T cell physiology
abnormal optic tract morphology
abnormal vascular smooth muscle physiology
abnormal vascular smooth muscle morphology
increased systemic arterial systolic blood pressure
vascular smooth muscle hypertrophy
enhanced NMDA-mediated synaptic currents
Abnormality of interleukin secretion
Monogenic Disease Association:
Not Detected
Polygenic Disease Association:
Not Detected
10K Immunome:
Not Detected
SARS-CoV-2 Association:
Not Detected
SARS-CoV-2 Vaccine Association:
Not Detected

Constructs for Lentiviral Expression

Basic Information

Gene Taxonomy:
CACNB3
Virus Type:
Lentiviral Vector
Vector Type:
cDNA
Construct ID:
IDG_CACNB3_OE_1

Selection:
Amp, Blasticidin

Vector:
lPX304

Construct Type:
Expression

Tag:
C terminal V5

Passed QC:
Yes

Sequence

Inserted_sequence:
ATGTATGACGACTCCTACGTGCCCGGGTTTGAGGACTCGGAGGCGGGTTCAGCCGACTCCTACACCAGCCGCCCATCTCT
GGACTCAGACGTCTCCCTGGAGGAGGACCGGGAGAGTGCCCGGCGTGAAGTAGAGAGCCAGGCTCAGCAGCAGCTCGAAA
GGGCCAAGCACAAACCTGTGGCATTTGCGGTGAGGACCAATGTCAGCTACTGTGGCGTACTGGATGAGGAGTGCCCAGTC
CAGGGCTCTGGAGTCAACTTTGAGGCCAAAGATTTTCTGCACATTAAAGAGAAGTACAGCAATGACTGGTGGATCGGGCG
GCTAGTGAAAGAGGGCGGGGACATCGCCTTCATCCCCAGCCCCCAGCGCCTGGAGAGCATCCGGCTCAAACAGGAGCAGA
AGGCCAGGAGATCTGGGAACCCTTCCAGCCTGAGTGACATTGGCAACCGACGCTCCCCTCCGCCATCTCTAGCCAAGCAG
AAGCAAAAGCAGGCGGAACATGTTCCCCCATATGACGTGGTGCCCTCCATGCGGCCTGTGGTGCTGGTGGGACCATCTCT
GAAAGGTTATGAGGTCACAGACATGATGCAGAAGGCTCTCTTCGACTTCCTCAAACACAGATTTGATGGCAGGATCTCCA
TCACCCGAGTCACAGCCGACCTCTCCCTGGCAAAGCGATCTGTGCTCAACAATCCGGGCAAGAGGACCATCATTGAGCGC
TCCTCTGCCCGCTCCAGCATTGCGGAAGTGCAGAGTGAGATCGAGCGCATATTTGAGCTGGCCAAATCCCTGCAGCTAGT
AGTGTTGGACGCTGACACCATCAACCACCCAGCACAGCTGGCCAAGACCTCGCTGGCCCCCATCATCGTCTTTGTCAAAG
TGTCCTCACCAAAGGTACTCCAGCGTCTCATTCGCTCCCGGGGGAAGTCACAGATGAAGCACCTGACCGTACAGATGATG
GCATATGATAAGCTGGTTCAGTGCCCACCGGAGTCATTTGATGTGATTCTGGATGAGAACCAGCTGGAGGATGCCTGTGA
GCACCTGGCTGAGTACCTGGAGGTTTACTGGCGGGCCACGCACCACCCAGCCCCTGGCCCCGGACTTCTGGGTCCTCCCA
GTGCCATCCCGGGACTTCAGAACCAGCAGCTGCTGGGGGAGCGTGGCGAGGAGCACTCCCCCCTTGAGCGGGACAGCTTG
ATGCCCTCTGATGAGGCCAGCGAGAGCTCCCGCCAAGCCTGGACAGGATCTTCACAGCGTAGCTCCCGCCACCTGGAGGA
GGACTATGCAGATGCCTACCAGGACCTGTACCAGCCTCACCGCCAACACACCTCGGGGCTGCCTAGTGCTAACGGGCATG
ACCCCCAAGACCGGCTTCTAGCCCAGGACTCAGAGCACAACCACAGTGACCGGAACTGGCAGCGCAACCGGCCTTGGCCC
AAGGATAGCTACTGCCCAACTTTCTTGTACAAAGTGGTTGGTAAGCCTATCCCTAACCCTCTCCTCGGTCTCGATTCTAC
GTAG

Media and Files

Snapgene File:
D.IC71-pLX304-CACNB3-expression-vector.dna

Constructs for CRISPR Interference

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